DNA Repair Protocols.pdf

DNA Repair Protocols true
By:Daryl S. Henderson
Published on 2006 by Springer Science & Business Media


In this second edition of a much praised laboratory manual devoted to eukaryotic systems, Daryl S. Henderson has refocused the book on mammalian cells, adding fourteen entirely new chapters and extensively revising many of the remaining chapters. The authors address a broad range of questions about practical mammalian DNA repair, including such arcana as |what is radioresistant DNA synthesis and how is it measured?| The techniques presented are readily reproducible and offer cutting-edge methods for cytogenetic analysis, measuring the cellular response to ionizing radiation, detecting single-strand (nicks) and double-strand DNA breaks, detecting the presence of |adducted| bases in DNA, and preparing mismatch repair (MMR) plasmid substrates. Among the highlights are excellent coverage of both base excision repair (BER) and nucleotide excision repair (NER), useful assays for identifying and quantifying UV-induced DNA lesions and DNA breakage, gene therapy, environmental mutagenesis and cancer, and gene targeting. The protocols follow the successful Methods in Molecular Biology series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Authoritative and highly practical, DNA Repair Protocols: Mammalian Systems, Second Edition, offers investigators a wide variety of productive methods to explore and make new discoveries in the world of mammalian DNA repair.

This Book was ranked at 26 by Google Books for keyword Repair.

Book ID of DNA Repair Protocols's Books is PTor-fMbBncC, Book which was written byDaryl S. Hendersonhave ETAG "MdicXoWUL7w"

Book which was published by Springer Science & Business Media since 2006 have ISBNs, ISBN 13 Code is 9781592599738 and ISBN 10 Code is 1592599737

Reading Mode in Text Status is false and Reading Mode in Image Status is true

Book which have "498 Pages" is Printed at BOOK under CategoryCytology

Book was written in en

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